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Genomics Core Laboratory

Overview of Services

Our mission is to provide UAMS investigators with convenient access to the latest technologies for genomic interrogation using Next Generation Sequencing (NGS), microarray, and ddPCR analysis.

The complete NGS service includes:

  • nucleic acid extractions & QC
  • library preparation & QC
  • sequencing instrumentation setup
  • bioinformatics QC
  • sequence alignment
  • molecular characterization of mutational findings
  • report generation (annotated Excel) 




Illumina Sequencers

  • NovaSeq 6000
  • NextSeq 500
  • MiniSeq

Illumina Bead Array

  • MethylationEPIC array for standard or FFPE DNA
  • Tecan Freedom EVO for high-throughput array staining
  • iScan and Autoloader for high-throughput array scanning

Nucleic Acid extraction

  • DNA & RNA from cells, solid tissues, & FFPE
  • cfDNA from plasma & urine

NGS Library Preparation

  • Whole Genome with NEBNext Ultra II
  • Targeted DNA panels with QIAseq
  • RNAseq with Truseq Stranded Total RNA
  • RNAseq with Truseq Stranded mRNA
  • RNAseq with Takara SMARTer Stranded Total RNA
  • single-cell RNAseq with 10X Genomics NextGEM 3'

QC for Nucleic Acids and NGS Libraries

  • Qubit fluorometer
  • NanoDrop spectrophotometer
  • Agilent Fragment Analyzer capillary elctrophoresis system
  • Library functional assessment with QuantStudio5 qPCR system

Droplet Digital PCR (ddPCR)

  • BioRad QX200 system

DNA Fragment Size Selection

  • Sage Science PippinHT



Donald J. Johann, MSc, MD

Ping Li
Operations manager



Location and hours of operation

Hours Location

Monday - Friday 

 8 AM - 5 PM

Winthrop P. Rockefeller Cancer Institute

University of Arkansas for Medical Sciences

4301 W. Markham St., slot # 753

Little Rock, AR 72205


Links and Resources

  1. UAMS Genomics Shared Resource Website
  2. Illumina coverage calculator




Name Role Phone Email Location
Donald Johann
Scientific Director

Ping Li
Operations Manager
(501) 526-6000 x 24316
Shijie Liu

Service list

Search available services: View: by category alphabetically
Nucleic Acid / Library handling (5)
NGS library preparation (8)
NGS Informatics (1)
Microarray (2)
Sequencing (13)
Consulting (1)
Droplet Digital PCR (1)